Brevundimonas vesicularis sepsis in a 2-month-old infant in rural Gambia: a case report
Abstract
Background: Brevundimonas vesicularis, a Gram-negative bacillus and non-lactose fermenter, is primarily found in both clinical and environmental samples. Although it rarely causes infections and is typically regarded as an opportunistic pathogen, it has been associated with cases of bacteremia, peritonitis, meningitis, arthritis, and skin infections. While there is high variability among cases, depending on site, infection severity, patient age, immune status, and geographic location, most cases occur in patients with underlying congenital conditions and immunocompromised individuals, which could represent an emerging global concern, particularly in low- and middle-income countries.
Case presentation: We present a 2-month-old African male infant who exhibited signs of sepsis and cyanotic congenital heart disease. The blood culture identified Brevundimonas vesicularis. Antimicrobial susceptibility testing was performed, and the bacterium was found to be sensitive to all the antibiotics evaluated. We treated the child with the empiric first-line antibiotics intravenous amoxicillin clavulanate and intravenous gentamicin for 6 days. The child improved and was referred for an echocardiogram and cardiology review.
Conclusion: This report details a rare case of B. vesicularis sepsis in a 2-month-old infant with congenital heart disease in the Gambia. B. vesicularis is an emerging pathogen linked to opportunistic infections in patients with congenital disorders and immunocompromised…
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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