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Catheter-Related Bloodstream Infection with Rhizobium radiobacter and Pseudomonas oryzihabitans Co-Infection: A Case Report and Literature Review

Huang HP, Liu PY, Huang PH

Antibiotics (Basel, Switzerland), 2025

Abstract

Background: Catheter-related bloodstream infections (CRBSIs) caused by environmental organisms are uncommon, and polymicrobial cases are even rarer. Methods: We describe the first case of catheter-related bloodstream infection caused by two infrequent environmental organisms-Rhizobium radiobacter and Pseudomonas oryzihabitans-occurring as a co-infection. Results: The patient's occupation involved frequent exposure to moist, soil-contaminated environments. Although these bacteria are often considered contaminants, they are capable of causing invasive infections such as bacteremia, which can be life-threatening. Conclusions: This case underscores the emerging pathogenic potential of R. radiobacter and P. oryzihabitans co-infection, particularly in patients with underlying malignancies or end-stage renal disease who have indwelling vascular devices, and highlights the importance of considering occupational and environmental exposures in the differential diagnosis of unusual pathogens.

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