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Chronic refractory ulcer caused by Edwardsiella tarda: a case report and literature review

Gu Q, Ma D, Wu Y, Wu W, Zou J, Zhang C

BMC infectious diseases, 2026

Abstract

Background: Post-traumatic Edwardsiella tarda (E. tarda) infections usually have an acute course. Chronic infection is rare. We report a chronic refractory ulcer caused by E. tarda after a freshwater stingray injury.

Case presentation: A previously healthy 32-year-old male diver sustained a stingray barb puncture wound to the right knee. The wound remained inflamed despite initial treatment and progressed to a deep ulcer with an 8-cm sinus tract. Bacterial culture confirmed E. tarda. Treatment included repeated surgical debridement, negative pressure wound therapy, and intravenous cefuroxime sodium based on susceptibility testing. The wound healed completely after three months, leaving a linear hypertrophic scar.

Conclusions: E. tarda infection should be considered in aquatic animal-related wounds, even in immunocompetent patients. Early pathogen identification, thorough debridement, and targeted antimicrobial therapy are essential.

Clinical trial number: Not applicable.

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