Antibiotic sensitivity to isolated bacteria in pediatric urinary tract infections
Abstract
Of the childhood urinary tract infections, more than 50% are caused by Escherichia coli (E Coli), followed by Proteus mirabilis (P mirabilis), Klebsiella sp, other enterobacteria, enterococci, Pseudomonas aeruginosa, and staphylococci. Of E coli isolates, 50 to 60% are resistant to ampicillin (ampi-R), 10% being susceptible to amoxicillin + clavulanic acid (AMC). For P mirabilis, ampi-R isolates are less frequent and more often susceptible to AMC. Klebsiella sp is resistant to ampicillin, 75% of isolates being susceptible to AMC. In these three species, the susceptibility of isolates to third generation cephalosporins, aminogly-cosides, and ciprofloxacin is still high (> 90%), but 15 to 35% are resistant to cotrimoxazole. In the other enterobacteria (Enterobacter cloacae, Morganella morganii, P vulgaris, Citrobacter freundii and Serratia marcescens) the resistance to cefalotin (hence to ampicillin and AMC) is permanent, with an exception: the susceptibility of P vulgaris to AMC. Enterococci are mostly susceptible to ampicillin, and P aeruginosa to ceftazidime, but in both species, the percentage of resistant strains in hospitalised patients is greater than in outpatients. For Staphylococcus aureus, the community-acquired isolates are susceptible to oxacillin and other anti-staphylococcal agents. All the coagulase negative staphylococci isolates are susceptible to vancomycin, but 70% of those from hospitalised patients are resistant to oxacillin, aminoglycosides and…
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