Antibiotic resistance pattern of enterococcal isolates from patients with urinary tract infection
Abstract
Background: Enterococci are the most common cause of healthcare associated urinary tract infections.The frequency of isolation of Enterococci from urinary tract of hospitalized patients has risen.Enterococcus is considered as an important nosocomial pathogen because of its intrinsic as well as acquired resistance to antibiotics.The purpose of this study is to determine the emergence of Enterococci as uropathogens and their antimicrobial susceptibility pattern.Materials and methods: This cross sectional study was conducted at the Department of Microbiology, A.C.S Medical College and Hospital.A total of 175 Enterococcus spp were isolated from patients with urinary tract infection.Identification and speciation of the Enterococcal isolates were done using conventional method.The antibiotic susceptibility testing of the Enterococcal isolates was performed by modified Kirby-Bauer disk diffusion method as per Clinical Laboratory Standard Institute (CLSI) guidelines.Results: A total of 175 urine specimens yielding the growth of Enterococci were studied.Enterococcus faecalis (77.7%) was the predominant species isolated followed by E. faecium (20%) and E. durans (2.3%).The sensitivity pattern of the isolates showed an increased resistance to antibiotics like erythromycin (66.3%), ciprofloxacin (56%) and penicillin (49.7%).The HLAR (High Level Aminoglycoside Resistance) to gentamycin was observed in 37.2%, however the susceptibility rate of nitrofurantoin was 86.9%, amoxicillin…
Read the paper
Related studies
- Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes
- Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant Escherichia coli
- Genomic Survey of E. coli From the Bladders of Women With and Without Lower Urinary Tract Symptoms
- Characterization of cefotaxime-resistant urinary Escherichia coli from primary care in South-West England 2017–18
- Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
- Emerging evidence-based innovative approaches to control catheter-associated urinary tract infection: a review
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.