Catheter-associated urinary tract infections in urethral stricture patients indwelling suprapubic catheter: Insights from a retrospective investigation into specific antibiogram and risk factors
Abstract
OBJECTIVES
This study aimed to evaluate the incidence and risk factors of suprapubic catheter-associated bacteriuria (SPCAB) and multidrug-resistant bacteria (MDRB) in patients with urethral strictures, and compare antimicrobial resistance patterns between pathogens isolated from urinary samples and suprapubic catheters.
METHODS
A retrospective analysis was performed on patients with urethral strictures who had urethral reconstructive surgery with suprapubic catheters from January 2010 to June 2023. Clinical data, bacterial pathogens, and resistance patterns were collected. Heatmaps visualized resistance profiles. Descriptive statistics summarized demographics and perioperative variables; while binary logistic regression models were applied to identify independent risk factors for SPCAB and MDRB.
RESULTS
Among 2809 urine samples, 42.6 % yielded positive cultures. The predominant pathogens in SPCAB were Escherichia coli (18.8 %) and Pseudomonas aeruginosa (11.9 %). Common pathogens exhibited high antimicrobial resistance rates, mirroring patterns observed in suprapubic catheter isolates. Risk factors for SPCAB included duration after suprapubic cystostomy (OR=1.712, P = 0.049), indwelling time of single catheter >15 days (OR=2.870, P = 0.007), absence of catheter colonization (OR=0.079, P 7 days. For MDRB, significant risk factors comprised duration after suprapubic cystostomy (OR=2.014, P = 0.009), indwelling time of single catheter >30 days (OR=2.541, P = 0.019), absence of…
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