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Management of antibiotics for urinary tract infections

Jana Rajtarova

reposiTUm (TU Wien), 2008

Abstract

Judicious prescriptions of antibiotic substances are becoming crucial as more and more bacterial resistances develop.Unavailable information about the etiology of infections results in applying broad-spectrum antibiotic substances, which foster the development of antibiotic resistances.The objective of this master thesis is to build a prototype of a computerized decision support system for aided prescription of antibiotic substances for urinary tract infections (UTIs) based on extended gathering of information on the incidence of pathogenic organisms and antimicrobial resistances in the respective medical institutions.For this purpose, data collected within MONI, a knowledge-based system for the early detection and continuous monitoring of nosocomial infections in operation at the Hygiene Department of the Vienna General Hospital, are exploited.From this retrospective patient database, records Abstrakt Sachgemäße und effektive Verschreibung von Antibiotika wird durch die Entwicklung neuer, resistenter Bakterien immer wichtiger.Fehlende Information über die Ursache einer vorliegenden Infektion resultiert oftmals in der Verschreibung von Breitbandantibiotika, welche die Entwicklung von Resistenzen fördern.Das Ziel dieser Arbeit ist es, einen Prototyp eines entscheidungsunterstützenden Systems für die Verschreibung von Antibiotika bei Harnwegsinfektionen (HWI) zu entwickeln, welcher auf gesammelter Information über die Inzidenz von Erregern und deren Resistenz basiert.Für…

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