MP29-12 in vitro and in vivo studies on bacteria and encrustation resistance of PLA-ciprofloxacin-coating ureteral stent application
Abstract
stones were seen (2), stones were too large (1), and the individual chose bilateral surgery instead (1). Nine participants with 11 stones received the research procedure: all tolerated treatment. Seven participants have received follow-up CT to date, 2 were stone free with 3 stones completely cleared. Mean reduction in stone volume was 70 (cid:3) 25%. Video recordings of the research procedures showed stone fragmentation and repositioning. Six of 9 provided photographs of passed fragments. AEs were mild and self-resolving and included: hematuria (6, average score 2.0 (cid:3) 1.6), renal colic (1), back pain (3), urinary urgency (1), and change in urinary frequency (1). One participant with a history of urinary tract infections was given antibiotics post procedure despite a negative urinalysis. All pain scores were zero, except one 2, which the participant attributed to positioning. CONCLUSIONS: It is feasible to remove small, asymptomatic, renal stones noninvasively in awake participants with only mild transient AEs. BWL and ultrasonic propulsion may in the not-too-distant future offer a way to prophylactically remove small stones before they require an emergency department visit or surgery.
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