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Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience

Biagio Pinchera, Elisa Schettino, Alessia D'Agostino, Emilia Trucillo, Federica Cuccurullo, Fabrizio Salemi, Amerigo Piccione, Rosa Carrano et al.

World Journal of Transplantation, 2025

2 citations

Abstract

BACKGROUND: Urinary tract infections (UTIs) in kidney transplant patients are a challenge. AIM: To evaluate epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients in a university hospital for UTI. METHODS: We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for UTI, with the objective to evaluate the epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients. RESULTS: From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection. CONCLUSION: Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.

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