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A Concise Review of Coenzyme Q10 Supplementation in The Preventative Treatment of Migraine

William Hoffman, Joshua D Luster, Rafaela Izurieta

Journal of medical case reports and reviews, 2022

Abstract

Migraine is a complex and heterogeneous syndrome that lacks clearly defined treatment. An effective prophylactic therapy with minimal side effect profile is of interest to patients and clinicians alike. CoEnzyme Q10, a critical member of the electron transport chain, has been proposed to play a role in the pathogenesis of migraine in certain patients. In this article, we provide a concise review of the proposed physiology of coEnzyme Q10 supplementation and its role in prophylaxis against pediatric and adult migraine. Robust data on this subject is lacking, though early evidence supports its routine use in clinical practice

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