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Global, regional, and national burdens and trends of migraine among males aged 10–59 years from 1990 to 2021: insights from the Global Burden of Disease study 2021

Haonan Zhao, Qing-Fang Wang, Zhang-Peng Chen, Wenxia Zhu

Frontiers in Neurology, 2025

4 citations

Abstract

Background Migraine, a prevalent neurological disorder, significantly impacts quality of life across populations. Although various demographic groups are impacted, existing research has focused predominantly on the general population, women, and adolescents, with insufficient emphasis on the burden experienced by men. This study aims to analyze data from the Global Burden of Disease (GBD) study spanning from 1990 to 2021, with the objective of elucidating the global prevalence, incidence, and disability-adjusted life years (DALYs) associated with migraine in males aged 10–59 years. Our investigation seeks to provide insights into this underexplored aspect of migraine’s impact over three decades. Epidemiological Transition refers to a shift in the burden of disease from communicable diseases to chronic non-communicable diseases, which in this study is reflected in the rising relative burden of migraine among men. Secondary Prevention (Secondary Prevention) reduces the frequency of migraine attacks through early diagnosis and intervention, e.g., use of prophylactic medications; Tertiary Prevention (Tertiary Prevention): reduces the degree of disability in diagnosed patients, e.g., cognitive-behavioral therapy. Results From 1990 to 2021, there was a significant increase in the burden of migraine among males aged 10–59 years worldwide. The number of incident cases rose by 46.55%, the number of prevalent cases rose by 56.54%, and the number of DALYs increased by 56.95%. The…

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Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

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