A study of clinical evaluation of migraine and other seizure related headaches in patients with Epilepsy - a prospective, cross-sectional, observational study
Abstract
Introduction Epilepsy and Migraine are the chronic disorders with recurrent neurological dysfunction associated with headache and autonomic, abdominal and psychotic features. In some patients it may be difficult to differentiate between migraine and the seizure episodes. Both are having comorbid symptoms and occurrence. Migraine patients can develop seizure and epileptics can have migraine attacks. Epileptologists proposed the hyperexcitability of the altered brain tissue, as the cause of seizure and migraine headache occurrence and vice versa. Enhanced hyperexcitability of cortical neurons and diminished threshold are the pathophysiological mechanisms enumerated in these conditions. Low magnesium in brain and the altered neurotransmitters are responsible for increased cortical excitability. Both the environmental as well as the genetic factors might cause these changes.
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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