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Risk factors and a nomogram model for recurrence of benign paroxysmal positional vertigo: a multicenter cross-sectional study

Qing-Chun Pan, Bei Li, Kai Zou, Jing Zhang, Yuanling Wang, Xiaoming Tang

Frontiers in Neurology, 2025

600 participants · 4 citations

Abstract

Objective To explore factors influencing the recurrence of benign paroxysmal positional vertigo (BPPV) within 1 year after treatment with canalith repositioning procedure (CRP) and to construct a risk prediction model with a nomogram. This model aims to offer a scientific basis for of high-risk groups’ early identification and to support the development of prevention strategies. Methods Data of BPPV patients diagnosed and successfully treated with CRP of 5 hospitals in Sichuan Province from Jan 2020 to Mar 2024 were retrospectively analyzed. The patients were divided into a training set of BPPV and a set of validation with a 7:3 ratio. After organizing the clinical data, the training set’s patients were arranged into recurrent and non-recurrent subgroups based on the recurrence of BPPV within one-year post-treatment. Factors affecting BPPV recurrence were found using LASSO regression; then, multivariate logistic regression (MLR) analysis was used to build a nomogram-style risk prediction model. The “receiver operating characteristic” (ROC) curve, Hosmer-Lemeshow calibration curve, clinical “decision curve analysis” (DCA), and clinical impact curve were employed to assess the model’s discrimination, accuracy, and clinical applicability. Results 600 patients in all were involved; 180 were in the validation set and 420 in the training set, following a 7:3 split. The overall recurrence rate of BPPV within 1 year was 39.17% (235/600 cases). The recurrence rates in the validation…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 600 participants or records.

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