Migraine and dietary factors: a narrative review of current evidence and clinical implications
Abstract
BackgroundDietary factors have been extensively examined as potential triggers or modulators of migraine episodes. Nevertheless, the current body of evidence concerning the influence of diet on the pathophysiology and management of migraines remains varied and occasionally contradictory.ObjectiveTo critically evaluate the existing evidence concerning the association between dietary factors and migraine, with a focus on potential triggers, dietary patterns, and the gut–brain axis.MethodsThis study employs a narrative review of the literature, concentrating on research that examines dietary triggers, nutritional interventions, and the pathophysiological mechanisms associated with migraine.ResultsCertain dietary components, including caffeine, chocolate, alcohol, and foods containing histamine, have been linked to the onset of migraine attacks in susceptible individuals, although findings remain inconsistent. Various dietary interventions—such as low-fat diets, ketogenic diets, low-glycemic diets, and diets enriched with omega-3 fatty acids—have demonstrated potential benefits in reducing the frequency and severity of migraines.ConclusionsDietary factors may affect migraine in a subset of patients through metabolic, inflammatory, and neurovascular pathways. Further well-designed prospective studies are necessary before definitive clinical recommendations can be formulated.
Read the paper
Related studies
- Bioactive Molecules Released in Food by Lactic Acid Bacteria: Encrypted Peptides and Biogenic Amines
- A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications
- Bioaccessibility and bioavailability of phenolic compounds
- The Glutamate Hypothesis in ALS: Pathophysiology and Drug Development
- Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery
- Effects of the Mediterranean Diet on the Components of Metabolic Syndrome Concerning the Cardiometabolic Risk
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.