An overview: role of phytochemicals in the prophylaxis of migraine
Abstract
Migraineis one of the most painful and debilitating conditionsencountered by 22.7% of peoplein Pakistan, thus many therapeutic strategies are being used to prevent and treat the symptoms and underlying pathology.Therole of phytochemicals inthe prevention of migraine attacks hasbeen studied at different research centersaround theworld formany years. It has been found that intake of food as well as phytochemicals containing antioxidants such as flavonoids, polyphenols and alkaloids are involved in the reduction of migraine episode frequency.The current literature supports the use of these plant derived substancestherefore if proven useful in other research including animal studies and human trials, can be given as an alternative or along with other prophylactic medical treatmentsso that better results can be yielded.Key Words:Migraine, Headache,Serotonin, Vasodilation
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