Oral magnesium supplementation: Bibliometric analysis of a century of scientific publication
Abstract
Oral magnesium supplementation has seen exponential growth in global consumption, driven both by advances on its metabolic roles and by increasing consumer demand. This bibliometric review systematically evaluates nearly a century of scientific production (1926–2024) on oral magnesium supplementation to characterise how the field has evolved and where critical evidence gaps remain. Analyzing 909 documents retrieved from the Web of Science Core Collection with the Bibliometrix R package, the results reveal an annual publication growth rate of 5.4%, with a marked increase in output after the 1980s. Research activity is geographically concentrated, with the USA and UK accounting for 38.6% of total citations. Thematic mapping highlights "hypomagnesaemia" as the central driving theme, alongside consolidated clusters in cardiometabolic and neurological health and emerging topics such as nanoparticle-based formulations. Despite this growth, relatively few studies have systematically evaluated the long-term adverse effects of magnesium supplementation or addressed environmental sustainability across the supplement life cycle . Furthermore, authorship and collaboration networks are concentrated within a limited set of journals and research groups, potentially constraining diversity of perspectives and innovation. Overall, these findings underscore the need for a more interdisciplinary and transparent research agenda, as well as robust randomised controlled trials that incorporate…
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