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Postpartum continuous epidural analgesia on pain, sleep quality, and emotional state in childbearing women: a randomized controlled trial

Jialei Zhang, Jing Li, Xiaoling Zhang, Jie Wu

Frontiers in Medicine, 2025

1 citation

Abstract

Objective This study aimed to explore the effects of continuous epidural analgesia on postpartum pain and sleep quality in postpartum women. Methods First-time mothers who received labor analgesia in the obstetrics department of Changzhi People’s Hospital, affiliated to Changzhi Medical College, from November 2024 to December 2024, were selected and randomly divided into the control group (C group) and the experimental group (E group). The control group received epidural labor analgesia after entering the labor process, using 10 mL of 1% ropivacaine, 50 μg of sufentanil, and 90 mL of 0.9% sodium chloride injection. The initial bolus dose was 6 mL, the injection rate was 6 mL/h, with additional doses of 4 mL each time, a lockout time of 15 min, and continuous infusion until the fetus was delivered and then stopped. The experimental group received epidural labor analgesia after entering the labor process and continued the infusion for 2 days after the fetus was delivered, with the same medication concentration and infusion rate as the control group. All postpartum mothers had blood samples taken before sleep on the 1st and 3rd days after delivery to measure serum melatonin levels. The visual analog scale (VAS) was used to compare pain scores (including sitting pain, sleep pain, and urination pain) on the 1st and 3rd days after the fetus was delivered in both groups. The modified Bromage score (MBS) was used to evaluate the mobility of the lower limbs. On the 3rd postoperative…

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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