Association between sleep quality in adolescence and dysmenorrhea severity in young adulthood: A prospective cohort study
Abstract
OBJECTIVE
To prospectively investigate the association between adolescent sleep quality and dysmenorrhea severity in young adulthood, and assess the moderating effect of initial dysmenorrhea status.
METHODS
We used data from 614 girls in the Amsterdam Born Children and their Development study. Sleep quality was assessed by Pittsburgh Sleep Quality Index (PSQI) at ages 15 to 16. Dysmenorrhea severity was assessed by modified Menstrual Disorder of Teenagers (MDOT) questionnaire at ages 19 to 20. Modified Poisson regression and multivariate logistic regression models were conducted to examine the association between overall sleep quality and its components and dysmenorrhea severity, while controlling for demographic, reproductive, psychosocial, and lifestyle factors. The moderation function of initial dysmenorrhea status was assessed by adding interaction term with sleep quality into models.
RESULTS
At ages 19 to 20, 77.7% (n=477) girls reported moderate/severe dysmenorrhea. At the beginning of the study, 45.5% (n=261) reported poor sleep quality at ages 15 to 16, of whom 84.3% (n=220) reported moderate/severe dysmenorrhea. Poor sleep quality (RR: 1.08, 95% CI: 0.99-1.19), global PSQI score (RR: 1.02, 95% CI: 1.01-1.04), longer sleep latency (RR: 1.05, 95% CI: 1.01-1.10), and lower sleep efficiency (RR: 1.11, 95% CI: 1.06-1.17) were associated with greater dysmenorrhea severity later in life. The effect of poor sleep quality was attenuated among girls with baseline dysmenorrhea…
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 477 participants or records.
Read the paper
Related studies
- Tryptophan Metabolism and Gut-Brain Homeostasis
- Rationale for a Multi-Factorial Approach for the Reversal of Cognitive Decline in Alzheimer’s Disease and MCI: A Review
- Prioritized Research for the Prevention, Treatment, and Reversal of Chronic Disease: Recommendations From the Lifestyle Medicine Research Summit
- Relationship between sleep disorders and gut dysbiosis: what affects what?
- The role of CLOCK gene in psychiatric disorders: Evidence from human and animal research
- Genetic, Transcriptome, Proteomic, and Epidemiological Evidence for Blood-Brain Barrier Disruption and Polymicrobial Brain Invasion as Determinant Factors in Alzheimer’s Disease
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.