P1084 Resting Energy Expenditure in Pediatric IBD: Discrepancies with Predictive Equations and Associations with Fatigue and Sleep Disturbances - A Cohort Study from a Regional Referral Centre
Abstract
Pediatric inflammatory bowel diseases (pIBD) are frequently associated with malnutrition and growth impairment. Assessment of resting energy expenditure (REE) may help optimize nutritional management. The aim of this study was to compare measured and predicted REE in pIBD, investigate its associations with clinical parameters, and evaluate daily energy intake, assessed by a 24-hour dietary recall, in relation to recommended reference intake levels.
REE was measured by indirect calorimetry and compared with Schofield predictive equations and LARN (Reference Intake Levels of Nutrients and Energy for the Italian Population) reference values in children with pIBD during follow-up. Clinical data and disease activity were collected. Standardized questionnaires assessed quality of life (IMPACT-III), perceived fatigue (Q6 and Q32 of IMPACT-III), physical activity (Physical Activity Questionnaire), and sleep quality (Pittsburgh Sleep Quality Index). In addition, we collected data using a 24-hour dietary recall to assess total daily energy intake.
Forty-five patients were included (26 males; 24 ulcerative colitis, 21 Crohn’s disease); 26 were in remission and 19 had active disease (mostly mild). Measured REE differed significantly from Schofield predictions (p = 0.015) and LARN reference values (p = 0.032, Figure 1a). A trend toward higher REE was observed in active disease. As expected, weight-normalized REE (REE/kg) showed a strong inverse association with BMI (p < 0.0001). REE was…
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Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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