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The association between Children's sleep quality and juvenile idiopathic arthritis

Linxia Li, Ya-Zhen Di, Zhan-Li Liu, Zelin Hao

Frontiers in Pediatrics, 2026

48 participants · 2 citations

Abstract

Objective To investigate possible sleep disturbances in children with juvenile idiopathic arthritis (JIA). Methods This case-control investigation evaluated 48 JIA patients vs. 90 healthy controls through comprehensive clinical assessments. Disease activity was quantified using the Juvenile Arthritis Disease Activity Score (JADAS-27), while health-related quality of life was measured with the Child Health Questionnaire (CHQ-PF28). Pain intensity was assessed through dual Methods: Visual Analog Scale (VAS) and Wong Baker Faces Scale. Fatigue levels were evaluated via the Pediatric Quality of Life Inventory Multidimensional Fatigue Scale (PedsQL-MFS), and sleep quality was analyzed using both the Children's Sleep Habits Questionnaire (CSHQ) and Sleep Disturbance Scale for Children (SDSC). All statistical analyses were conducted in SPSS 26.0, employing independent t-tests for intergroup comparisons and Spearman correlation analysis for variable relationships. Results The incidence of sleep disturbance was significantly higher in the JIA group (P < 0.01). CSHQ assessments reveal abnormal total scores and six subdomains (sleep duration, daytime sleepiness, etc.; all P < 0.05), with specific correlations: total scores link to disease activity (JADAS-27/AJC; P = 0.021–0.05), shortened sleep duration strongly associates with ESR/functional status (P = 0.002/0.006), and daytime sleepiness connects to physician global assessments (PGA/PGE; P = 0.017–0.029). SDSC evaluations indicate…

How strong is the evidence?

Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 48 participants or records.

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