Sleep quality in infants with atopic dermatitis: impact of lesion location and disease severity in a retrospective cross-sectional study
Abstract
Atopic dermatitis (AD) is a common inflammatory skin disorder in infants and is frequently associated with sleep disturbances. Although the relationship between disease severity and sleep quality is well established, the effect of lesion localization on sleep has not been thoroughly investigated. This retrospective cross-sectional study included 60 infants aged 6–36 months diagnosed with AD and 60 age-matched healthy controls. Sleep quality was assessed using the Children’s Sleep Habits Questionnaire (CSHQ), which, although originally developed for older children, has been used in younger populations in previous studies. Disease severity was evaluated using the Scoring Atopic Dermatitis (SCORAD) and Patient-Oriented Eczema Measure (POEM) indices. Lesion localization was determined through clinical examination and categorized as face/neck, trunk/extremities, or generalized (involvement of two or more regions). Parametric and nonparametric tests were used for intergroup comparisons. Relationships between variables were examined using Spearman’s correlation analysis, and multivariate regression analysis was employed to identify independent associations. The AD group exhibited significantly higher total CSHQ scores (p < 0.001). Sleep onset latency, night awakenings, bedtime resistance, and sleep duration problems were more pronounced in infants with AD. Positive correlations were observed between SCORAD/POEM scores and CSHQ scores (p < 0.001). Infants with facial and neck…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 60 participants or records.
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