1024 Prevalence of Sleep Concerns and Sleep Hypnotic Use in Children with Rare Neurogenetic Conditions
Abstract
Sleep disturbances are common in the pediatric population and contribute to significant stress on both the child and their care providers. Sleep has been linked to early brain development and learning, and poor sleep has been shown to contribute to behavioral problems and attention concerns. While some sleep disturbances are known to be associated with specific genetic conditions, their overall prevalence in children with rare neurogenetic conditions remains to be quantified.
Retrospective chart review was performed of all new patient consultations at a pediatric neurogenomics clinic in a sixth month period. Charts were queried for sleep concern based on prevalence of the following criteria: previous or current evaluation for sleep disordered breathing, spontaneous patient or caregiver complaint of sleep disturbance, or prescription for sleep hypnotic medication.
Of the fifty nine pediatric patients seen for new consultations 33.9% were identified as having sleep concerns. Most prevalent concern was insomnia, though sleep apnea, excessive daytime sleepiness, and parasomnias were also identified. Some caregivers and patients identified multiple concerns. Of the seventeen patients with insomnia concerns identified, seven were already prescribed medication for sleep hypnotic benefit. It was noted in all of these patients insomnia was identified as a persistent concern. Sleep hypnotics utilized included clonidine, trazodone, guanfacine, and clobazam (utilized concurrently for…
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