0775 Sleep Timing in Children and Adolescents with Functional Abdominal Pain Disorders
Abstract
Functional abdominal pain disorders (FAPD) are among the most common chronic pain conditions in childhood, affecting 25% of children worldwide and accounting for about 50% of pediatric gastroenterology visits. Self-reported sleep disturbances with impaired functioning have been reported in FAPD patients, however, objective sleep measures, specifically circadian rhythm disruptions, are scarce. Hence, we aimed to objectively characterize the sleep quality, duration, and timing of children with FAPD compared to healthy controls.
Patients who met the criteria for FAPD through the Rome 4 diagnostic questionnaire were recruited throughout the year from the Disorders of Gut Brain Interaction (DGBI) Clinic at CCHMC. Healthy controls aged 11-18 years, matched in demographic variables (BMI, race, gender) with cases, were recruited in a 1:1 ratio. Demographic information, medications (including timing), dietary patterns, school schedule, validated questionnaires (ASWS: Adolescents Sleep-Wake Scale, PISI: Pediatric Insomnia Severity Index) and other medical comorbidities were collected in cases and controls. Subjects were sent home with an actiwatch (Philips Respironics) to complete actigraphy assessments for 7 days.
Youth with FAPD (n= 26) subjectively reported significantly poorer sleep quality and insomnia severity than controls (n=28) on questionnaires (p.05). Compared to controls, youth with FAPD had notably delayed sleep timing on actigraphy, measured by the sleep midpoint…
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