Melatonin and clinical application
Abstract
A review of the different publications dealing with melatonin in humans shows that this field has been very active in the last few years.Normative melatonin values have been defined.Various relationships between melatonin and other traits have been studied, such as sleep, circadian rhythm, surgical stress and anaesthesia.Age-related melatonin studies and melatonin during depression and other psychiatric disorders have been reviewed.Finally, some studies have been performed to use melatonin as a medication for sleep disturbance in depression, for jet-lag and as a skin protector for ultraviolet light.© Inra/Elsevier, Paris melatonin / clinics / depression / sleep / circadian Résumé ― Mélatonine et applications cliniques.Une revue des différentes publications traitant de la mélatonine chez l'homme montre que ce champ a été très actif au cours de ces dernières années.Des normes de concentrations de mélatonine ont été définies.Diverses relations entre la mélatonine et d'autres caractéristiques comme le sommeil, les rythmes circadiens, le stress chirurgical et l'anes- thésie ont été étudiées.Des études sur la mélatonine au cours du vieillissement et sur la mélatonine pendant la dépression et au cours d'autres désordres psychiatriques ont été conduites.Enfin, plusieurs essais ont utilisé la mélatonine comme médicament pour traiter les troubles du sommeil pen- dant la dépression, pour atténuer le jet-lag et comme protecteur de la peau contre les UV. © Inra/
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