Impact of SARS-CoV-2 on Sleep / Wake Cycle and Melatonin
Abstract
The world has come to a halt as a result of the SARS-CoV-2 pandemic, which has forced most countries to implement lockdown for the maintenance of the spread of infection. This commentary highlights the important role of sleep as a public health problem, especially in stressful life stages such as the COVID-19 pandemic, and is evidence-based and practical for managing sleep disorders during this crisis. People’s routine has changed due to lockdown, including physical activities, eating habits, electronic usage, and sleeping habits. This has caused disruption between the external and internal zeitgebers and have the greatest impact on melatonin hormone. Melatonin is a key regulator of sleep-in body and controls other hormone cycles as endogenous synchroniser. Sleep is influenced by both circadian and homeostatic factors and sleep problems have a wide range of impacts on the body, effecting different physiological system. So, we should maintain a sleep / wake cycle which will benefit the overall health.
Read the paper
Related studies
- Tryptophan Metabolism and Gut-Brain Homeostasis
- Rationale for a Multi-Factorial Approach for the Reversal of Cognitive Decline in Alzheimer’s Disease and MCI: A Review
- Prioritized Research for the Prevention, Treatment, and Reversal of Chronic Disease: Recommendations From the Lifestyle Medicine Research Summit
- Relationship between sleep disorders and gut dysbiosis: what affects what?
- The role of CLOCK gene in psychiatric disorders: Evidence from human and animal research
- Genetic, Transcriptome, Proteomic, and Epidemiological Evidence for Blood-Brain Barrier Disruption and Polymicrobial Brain Invasion as Determinant Factors in Alzheimer’s Disease
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.