Role of Omega 3 Fatty acids, Vitamin D, Vitamin B12, Vitamin B6 and Folate in Mental wellbeing- A Short review of Literature
Abstract
Neuropsychiatric conditions have been linked to around 14 percent of the global disease burden, mainlydue to the chronically debilitating nature of depression and other widespread mental disorders, alcohol anddrug use disorders, and psychosis. The science and lay press have confirmed that vitamin D is an importantfactor that can have major health benefits in the prevention and treatment of many chronic diseases. Mostpeople have inadequate vitamin D levels in this country. This is also relevant for people with depression andother mental illnesses as well. Inadequate food consumption, lifestyle or other factors are a major causes ofVitamin D deficiency. Successful diagnosis and treatment of insufficient levels of vitamin D in people withdepression and other mental illnesses could be a simple and cost-effective therapy that could enhance thelong-term health outcomes and quality of life of patients. It is now well known that omega-3 fatty acids areimportant for physical health, and there is growing evidence that omega-3 fatty acids may also be importantfor mental health. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), the two major omega-3fatty acids in fish oil, have essential biological roles within the CNS. DHA is a major structural componentof neuronal membranes, and modifying the neuronal membrane fatty acid composition contributes tofunctional changes in the behaviour of phospholipid membrane-embedded receptors and other proteins.EPA has major physiological…
Read the paper
Related studies
- Promising Sources of Plant-Derived Polyunsaturated Fatty Acids: A Narrative Review
- Effects of omega-3 polyunsaturated fatty acid intake in patients with chronic kidney disease: Systematic review and meta-analysis of randomized controlled trials
- Effect of omega-3 fatty acids on cognition: an updated systematic review of randomized clinical trials
- The role of omega-3 polyunsaturated fatty acid supplementation in the management of type 2 diabetes mellitus: A narrative review
- Paucity of evidence for a relationship between long-chain omega-3 fatty acid intake and chronic obstructive pulmonary disease: a systematic review
- Omega-3 fatty acid nanocarriers: Characterization and potential applications
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.