Open Trial Determining Antidepressant Effects of Omega-3 Supplementation During Pregnancy
Abstract
The purpose of this study is to determine if omega-3 polyunsaturated fatty acids as a monotherapy have antidepressant effects during pregnancy. It will also provide pilot data pertaining to relationships between apparent response to omega-3 monotherapy and both plasma cytokine and erythrocyte essential fatty acid concentrations.
Conditions: Major Depressive Disorder in Pregnancy.
Primary outcome: The Hamilton Rating Scale for Depression (HAM-D); Montgomery-Asberg Depression Scale (MADRS); Edinburgh Postnatal Depression Scale (EPDS); Beck Depression Scale (BDI).
Enrollment: 3 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 3 participants or records.
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