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A bibliometric analysis of global research status and trends in irritable bowel syndrome and gut microbiota metabolites

Wang SR, Zhou J, Zhang JY, Li SF, Hu GJ

Frontiers in microbiology, 2025

1 citation

Abstract

Background: Metabolites derived from the gut microbiota are substantial contributors to the pathophysiology of Irritable Bowel Syndrome (IBS). As our understanding of the mechanisms underlying gut microbiota metabolites advances, significant progress has been made in research exploring the correlation between gut microbiota metabolites and IBS. Nevertheless, a comprehensive synthesis of research foci and trends in this domain is still lacking. Consequently, integrating scientometric methods with a range of analytical tools can facilitate the identification of key research areas and potential future study directions.

Methods: The present study employed scientometric tools, including VOSviewer, Bibliometrix software, CiteSpace, Tableau, and R software, to collect and analyze research literature on IBS and gut microbiota metabolites. This comprised an analysis of journal publications and their impact, the identification of prolific authors, the establishment of national research collaboration networks, and the co-occurrence analysis of keywords.

Results: The analysis revealed that, following screening, a total of 1,489 documents were obtained, with a gradual increase in the number of publications starting from 2006. The United States, China, and the United Kingdom have been identified as the primary hubs of this research field. The leading research institutions were identified as University College Cork, the Mayo Clinic, and the University of California. In the domain of…

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