Impact of MIND diet on cognitive function among patients with metabolic syndrome: a randomised control clinical trial
Abstract
BACKGROUND: Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet is a new dietary approach designed to help maintain cognitive function. Patients with MetS are at increased risk of cognitive decline due to chronic inflammation, oxidative stress, and vascular dysfunction. Therefore, this population provides an appropriate model to investigate the potential neuroprotective effects of the MIND diet, which emphasizes foods with anti-inflammatory and antioxidant properties. AIMS: This study aims to investigate the impact of this diet on the cognitive function of patients with MetS. METHODS: This research was a RCTs conducted with adults diagnosed with MetS who were referred to the Hazrat Ali Health Center in Isfahan. A total of 56 eligible participants were divided into two groups: one group received the MIND diet along with a placebo, while the other served as a control group. Statistical analysis was performed using SPSS26. RESULTS: In this study, we compared the two groups. The MIND diet group showed a significant increase in total cognitive function after adjusting for Model 1 [Using Generalized Linear Model (GLM) with distribution of Gamma & link of Log controlling for baseline, gender, education, surgery, drug, supplementation, physical activity, age, and hospitalization] and 2 [Using Generalized Linear Model (GLM) with distribution of Gamma & link of Log controlling for baseline, gender, education, surgery, drug, supplementation, physical activity, age,…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 56 participants or records.
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