Evidence Hub

A Novel Chronotype-Based Mediterranean Diet Pyramid: An Updated Representation by the Italian Society of Endocrinology (SIE) and the Italian Society of Dietetics and Clinical Nutrition (ADI)

Barrea L, Verde L, Camajani E, Annunziata G, Mollica MP, Minnetti M, Trinchese G, Losignore P et al.

Current nutrition reports, 2026

2 citations

Abstract

PURPOSE OF REVIEW: This review explores the integration of chronobiology and chronotype-specific factors into the Mediterranean Diet (MD) framework. While the MD is widely recognized for its cardiometabolic and neuroprotective effects, current guidelines do not address the timing of food intake or the influence of individual chronotype. Given the growing evidence linking circadian alignment, meal timing, and metabolic health, we propose a revised Mediterranean Diet pyramid tailored to chronotype and lifestyle determinants, herein referred to as the chronotype-based Mediterranean Diet Pyramid of the Italian Society of Endocrinology (SIE) and the Italian Society of Dietetics and Clinical Nutrition (ADI). RECENT FINDINGS: Chrononutrition emphasizes the timing, frequency, and regularity of meals as key elements for metabolic regulation. Early-day energy intake, time-restricted eating, and alignment with circadian rhythms improve glycemic control, weight management, and cardiovascular outcomes. Morning chronotypes tend to show higher adherence to the MD, whereas evening chronotypes more frequently delay meals, skip breakfast, and consume energy-dense foods at night, contributing to poorer metabolic profiles. Sleep duration and quality further modulate appetite regulation and dietary adherence. Building on these insights, the proposed pyramid integrates circadian cues, represented by sun and moon symbols, to guide nutrient timing. Foods rich in carbohydrates and fiber (whole…

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free