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The Efficacy of Nutritional Interventions in Reducing Childhood/Youth Aggressive and Antisocial Behavior: A Mixed-Methods Systematic Review and Meta-Analysis

Konkolÿ Thege B, Robitaille C, Mahmoud L, Kinzel EA, Qamar R, Hartmann-Boyce J, Choy O

Campbell systematic reviews, 2025

2,109 participants · 1 citation

Abstract

Aggressive/antisocial behaviors in children and youth may result in impairments in family, social, or academic functioning and lead to long-term negative consequences for both the individual and society as a whole. The potential of healthy diet and nutritional supplements to reduce aggression and antisocial behavior is an active area of study in nutritional mental health sciences. The goal of this systematic review is to (1) investigate the effectiveness/efficacy of nutritional interventions (dietary manipulation, fortification or supplementation) in reducing excessive aggression, antisocial behaviors, and criminal offending in children/youth (systematic review and meta-analysis); and (2) provide an overview of implementation barriers and facilitators regarding nutritional interventions in children/youth (qualitative/narrative synthesis). After consulting the Campbell Collaboration's methodological guidelines, a comprehensive search for published and unpublished papers on controlled intervention studies was performed (up to February 26, 2024) using both electronic databases (MEDLINE, Embase, Cochrane Library, APA PsycInfo, Scopus, and the Allied and Complementary Medicine Database) and other resources (e.g., Google Scholar, reference list of included studies and other reviews, websites of public health agencies). This study focuses on children and youth (up to the age of 24) presenting with an above-average level of aggression/antisocial behavior. In terms of the…

How strong is the evidence?

Evidence Hub reads this as a meta-analysis. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 2,109 participants or records.

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