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Role of Omega-3 Fatty Acids and Autism Spectrum Disorder: A Systematic Review

Dur E Shehwar Ali, Fazlina Shaid, Madiha Khattak, Ayesha Qaiser, Saman Tauqir, Shayan Ali Shah

Pakistan Journal of Medical & Cardiological Review, 2024

Abstract

This systematic review examines the relationship between omega-3 supplementation and autism spectrum disorders (ASD). A comprehensive literature search was conducted across multiple databases, including PubMed, Cochrane Library, Web of Science, EMBASE, and relevant articles published since 2010. Following systematic screening, 10 clinical controlled studies met inclusion criteria. The review assessed intervention effects on ASD core symptoms, including social interaction, behavioral functioning and speech function. The findings indicate that omega-3 supplementation alone has minimal impact on alleviating ASD core symptoms.

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Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

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