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Clinical factors associated with postoperative fever after bipolar TURP and GreenLight laser vaporization: a retrospective cohort study

Huang L, Guo F, Liu C, Bai S, Chen Y, Bao Q, Luo X, Zhu J et al.

Frontiers in surgery, 2026

401 participants

Abstract

Background: Postoperative fever after transurethral surgery for benign prostatic hyperplasia may prompt evaluation for infection, but interpretation is complicated by catheterization, perioperative inflammation, variable microbiological sampling, and procedure-specific differences.

Methods: We retrospectively analysed 401 patients who underwent bipolar transurethral resection of the prostate (bTURP) or GreenLight laser photoselective vaporization of the prostate (GL-PVP) from October 2019 to February 2023. The primary outcome was postoperative fever recorded during the index admission. Multivariable logistic regression was used to identify associated factors. Post hoc model checks included assessment of multicollinearity, calibration, goodness of fit, discrimination, and five-fold internal cross-validation where feasible. Available postoperative culture and antimicrobial susceptibility records were analysed descriptively.

Results: Postoperative fever was recorded in 48 of 401 patients (11.97%), with no significant difference between bTURP and GL-PVP (11.44% vs. 12.73%; P = 0.755). In the reported multivariable model, diabetes mellitus, a positive preoperative urine culture, preoperative lower urinary tract functional testing, preoperative indwelling catheterization, and longer operative time were associated with postoperative fever. Post hoc diagnostics showed no severe multicollinearity and acceptable apparent discrimination, but the limited number of events supports…

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 401 participants or records.

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