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Pharmacoeconomical Analysis of Pazufloxacin and Levofloxacin in Treatment of Urinary Tract Infection

Wan-Ping Ye

2007

Abstract

Objective:To analyze the cost-effectiveness of pazufloxacin and levofloxacin in treatment of urinary tract infection. Methods: 70 cases with urinary infection were randomly divided into 2 groups,in which they were treated with pazufloxacin and levofloxacin, respectively. The cost-effectiveness in two groups was analyzed and compared with each other by pharmacoeconomical methods. Results: There was no significant diffe-rence in therapeutic effect between two groups(P0.05),such as effective rates of 94.3% and 88.6%,bacterial clearance rates of 91.4% and 85.7% and undesired event rates of 5.71% and 8.57% in pazufloxacin group and levofloxacin group.However,there was significant difference in cost-effectiveness ratio between two group,16.96 and 9.30 respectively in pazufloxacin group and levofloxacin group (P0.05). Conclusion: Levofloxacin has cost-effective advantage over pazufloxacin in the treatment of urinary tract infection.

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