Clinical effect of levofloxacin combined with ceftazidime on treatment of infections in patients with advanced urinary tract tumors
Abstract
OBJECTIVE To explore the effect of levofloxacin combined with ceftazidime on treatment of infections in patients with advanced urinary tract tumors and summarize clinical experience so as to provide theoretical basis for treatment of the advanced urinary tract tumor patients with infections.METHODS A total of 120 patients with advanced urinary tract tumors who were treated in the hospital from Aug 2006 to Feb 2014 were randomly recruited as the study objects and divided into two groups,with 60 cases in each;the clinical data of the two groups of patients had significant difference and were comparable;the group A was treated with levofloxacin,while the group B was given the levofloxacin combined with ceftazidime,with the treatment cycle of 14days;the effect on treatment of infections and the incidence of adverse reactions were observed and compared between the two groups.RESULTS Totally 22(36.7%)cases were cured in the group A,25(41.7%)cases in the group B;28(46.7%)cases were effective in the group A,32(53.3%)cases in the group B;7(11.7%)cases were improved in the group A,2(3.3%)cases in the group B;the total effective rate was 83.3%in the group A,95.0%in the group B;3cases were ineffective in the group A,1case in the group B;the clinical efficacy of the group B was significantly better than that of the group A(P0.05).The mild adverse reactions occurred in both groups during the drug therapy and disappeared after withdrawal of drugs,and there was no significant difference in…
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