Randomized controlled study on gatifloxacin and levofloxacin injection in the treatment of acute gonococcal urinary and reproductive tract infections
Abstract
目的:加替沙星注射液在治疗急性淋菌性泌尿生殖道感染中的有效性和安全性.方法:采用随机双盲对照试验,以左氧氟沙星为对照药物,共治疗急性淋菌性泌尿生殖道感染38例,加替沙星组和左氧氟沙星组各19例.治疗方案均为静脉输注每次0.2g,一日两次,疗程7～14天.结果:试验组临床治愈率、有效率和淋菌清除率均为100%,对照组分别为96.2%、100%和100%.对合并的支原体、衣原体感染的清除率试验组为100%,而左氧氟沙星组为85.71%和100%,两组无统计学差异(P＞0.05).两组均无明显不良反应发生.结论:加替沙星治疗急性淋菌性泌尿生殖道感染的有效性和安全性与左氧氟沙星相似.
How strong is the evidence?
Evidence Hub reads this as a randomized trial. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.