Urinary Tract Infection in Elderly: Clinical Profile and Outcome
Abstract
OBJECTIVE: Urinary tract infection (UTI) being the most common bacterial infection with considerable morbidity and mortality especially in hospitalized geriatric patients, this study was designed to assess clinical profile, predisposing factors, uropathogen profile causing UTI and to identify associated factors responsible for mortality.
METHODS: :Prospective observational study was undertaken among elderly patients aged ≥ 60 years in a tertiary care hospital. 95 indoor patients from medicine wards having symptoms of UTI and urine culture showing significant growth were included in the study. Demographic profile, clinical features, predisposing factors, laboratory features, urine culture reports, antimicrobial susceptibility patterns and outcome were noted and analysed.
RESULTS: Of the 95 patients studied, 55.78% were males. 50.52% patients were in age group of 61 to 70 year. Frequency of micturition was the major symptom. Diabetes mellitus was the most common predisposing factor associated with UTI seen in (46.31%) patients. Gram negative organism accounted for 88(92.63%) of bacterial isolates, with Escherichia coli seen in 47.36% of cases. Non-E.coli gram negative organisms such as Pseudomonas, Klebsiella showed lower sensitivity to Levofloxacin, Piperacillin + Tazobactam, Amikacin and Ceftazidime. Mortality rate was 17.89%. Significantly higher mortality was seen in patients with diabetes mellitus (p1.4 mg/dl ((p<0.0001) and increasing number of predisposing factors.…
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 95 participants or records.
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.