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Antimicrobial use in post-acute care: a retrospective descriptive analysis in seven long-term care facilities in Georgia

Richards CL, Darradji M, Weinberg A, Ouslander JG

Journal of the American Medical Directors Association, 2005

53 participants

Abstract

BACKGROUND: Antimicrobial use in long-term care facilities (LTCF) is an important public health issue, especially regarding its potential role in antimicrobial resistance. Up to two thirds of long-stay LTCF residents receive antimicrobial therapy each year. However, little is known specifically about antimicrobial use in short-stay LTCF residents receiving post-acute care.

METHODS: The authors conducted a retrospective chart review of a random sample of residents admitted for post-acute care in seven LTCFs in Georgia from September 1, 1999 to August 31, 2000 to determine the rates and characteristics of antimicrobial prescribing in this population.

RESULTS: Of 221 post-acute care residents, 105 (48%) received 152 courses of antimicrobial therapy during their post-acute stay. At least one antimicrobial was prescribed on 796 of 5220 resident-days (15%). Antimicrobial therapy was split evenly between hospital-initiated antimicrobial therapy (n = 53, 50%) and antimicrobial therapy initiated in the LTCF during post-acute care (n = 52, 50%). Levofloxacin was the most commonly prescribed antimicrobial. Where documentation on the suspected infection was present, the most common infections were urinary tract infections (UTIs) and pneumonias. For residents with post-acute care-initiated therapy, documentation regarding the presumed source of infection was absent for 44% of antimicrobial prescriptions. Most antimicrobial courses initiated for presumed infections in post-acute care were…

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 53 participants or records.

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