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Antimicrobial susceptibility pattern of bacteria isolated from urinary tract infection among undergraduate students at Benson Idahosa University

I. Ehiaghe, B. Osaro

Scientific African, 2025

Abstract

Urinary tract infections (UTIs) are common among university students and are increasingly complicated by antimicrobial resistance, making effective treatment challenging. This study aimed to determine the prevalence of bacterial UTIs and the antimicrobial susceptibility patterns of isolates among undergraduate students at Benson Idahosa University. A cross-sectional study was conductedinvolving 120 undergraduate students. Midstream urine samples were collected aseptically and cultured on CLED and MacConkey agar to isolate uropathogens. Bacterial identification was performed using conventional biochemical tests. Antimicrobial susceptibility testing was carried out using the Kirby-Bauer disk diffusion method. Sociodemographic data and sexual activity status were collected through structured questionnaires. The overall UTI prevalence was 24.3%, with the highest rate in the 24–27 years age group. Females had a higher infection rate (25.7%) than males (13.3%), though this was not statistically significant. Sexual activity was significantly associated with UTI prevalence (p = 0.013). Among the 29 isolates recovered, Staphylococcus aureus (34.5%) was most frequent, followed by Klebsiella spp. (24.2%) and Escherichia coli (20.7%). Gram-negative isolates showed high susceptibility to gentamicin (83.3%–100%) and levofloxacin (50%–100%), but high resistance to cefixime, cefotaxime, imipenem, and cefuroxime. S. aureus demonstrated susceptibilityto gentamicin (80%) and levofloxacin (70%)…

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Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.

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