Risk factors and antibiogram of human uropathogens in the northern part of Bangladesh: A cross-sectional study
Abstract
Multidrug-resistant (MDR) bacteria are a significant public health hazard for individuals with urinary tract infections (UTIs). This study identified, described, and classified antibiotic-resistant bacterial uropathogens in human urine samples and examined them for UTI risk factors. Between November 2020 and December 2021, 256 suspected UTI patients from the Popular Diagnostic Centre Ltd., northern Bangladesh, were studied. A well-structured questionnaire assessed sociodemographic parameters and risk factors. Early morning urine samples were examined bacteriologically for bacterial isolates. The Kirby-Bauer disk diffusion method evaluated bacterial isolates’ susceptibility to 22 commonly used antibiotics. The frequency of UTIs was 51.56%. The infection rate was higher in females (64.40%) than in males (26.51%). Escherichia coli (41.66%), Enterococcus faecalis (23.48%), and Klebsiella pneumoniae (18.93%) were the predominant uropathogens. Antibiograms revealed that imipenem, meropenem, amikacin, netilmicin, nitrofurantoin, gentamicin, moxifloxacin, levofloxacin, and cefepime were effective against the isolated bacteria. Most bacterial strains were resistant to linezolid, cephradine, azithromycin, nalidixic acid, cefuroxime sodium, co-trimoxazole, cefixime, and ceftriaxone. The isolates had a MDR rate of 88.6%. Age, place of residence, marital status, and prior antibiotic use were statistically associated with MDR UTIs. UTI patients often have MDR bacteria in their urine,…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 256 participants or records.
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.