Urinary Tract Infection with Esherichia coli and Antibacterial Activity of Some Plants Extracts
Abstract
Urinary tract infections are the most common pathogenic infections, these infections lead to many difficult problems, especially increasing resistance to antibiotic drugs. Generally humans in many countries, especially developing countries expose to urinary tract infection in different ages and sex. The aim of this study was to evaluate the antibacterial activities of natural extracts against pathogenic E. coli causing urinary tract infections. A total 130 urine samples was collected from patients examined for urinary tract infection in King Abdulaziz University Hospital, Urology Department, Saudi Arabia. Results indicated a positive bacterial growth on cled, macConkey's agar and nutrient agar. E. coli was the most predominant pathogen causing urinary tract infection with ratio 43.9%. The incidence of bacteriuria was higher among patients ages 41-52 years old (35.3%) and decrease to 15.5% with age of 29-40 years old and less incidence was detected among 77-87 years old (1.7%). Also, the infection was more prevalent among females (56.9%) compared to males (43.1%). Ciprofloxacin, levofloxacin and norfloxacin were the best antibiotics used against E. coli isolates. Clove, ginger (dry, fresh), peppermint, spearmint and thyme alcoholic extracts were the most effective plant extracts against selected isolates of E.coli. It was concluded that combination between clove alcoholic extract and antibiotics as gentamicin, levofloxacin, amikacin and norfloxacin increase the synergistic…
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