In Vitro Antibacterial Activity of Honey against Clinical Isolates Associated With Urinary Tract Infections
Abstract
Honey has been used as a traditional remedy for microbial infections since ancient times. With increasing concerns about antibiotic resistance, there is growing interest in evaluating natural products like honey for their antimicrobial properties. This study investigates the antibacterial activity of honey against Staphylococcus aureus and Escherichia coli, two common pathogens responsible for urinary tract infections (UTIs). Honey samples were obtained from local commercial producers in Bauchi State, Nigeria. The samples were diluted to concentrations of 25%, 50%, 75%, and 100% (v/v). Clinical isolates of S. aureus and E. coli were obtained from UTI patients and confirmed using standard microbiological techniques. Antibacterial activity was assessed using the agar well diffusion method. Mueller-Hinton agar plates were inoculated with standardized bacterial suspensions, and wells were filled with different honey concentrations. Gentamicin (10µg) and Ofloxacin (5µg) were used as control antibiotics. Plates were incubated at 37°C for 24 hours, and inhibition zones were measured. The undiluted honey (100% concentration) exhibited the highest antibacterial activity against all tested bacteria. The inhibition zones ranged from 16–24 mm for S. aureus and 19–22 mm for E. coli across different honey concentrations. The antibacterial activity of honey was superior to Gentamicin but comparable to ofloxacin. Statistical analysis showed no significant difference (P>0.05) between the…
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.