Microbiological Profile of Urinary Tract infections among Patients attending a Tertiary care Hospital
Abstract
Background: UTI is a common infection among all age groups.Timely detection and management of urinary tract infection is important as it leads to varied morbidity and mortality.Causative agents of UTI are E.coli, Klebsiella spp, Proteus spp, Pseudomonas spp, Staphylococcus spp, Enterococcus spp.In recent years resistance has been seen to various antibiotics used to treat urinary tract infection.Therefore, it is important to know the antibiotic profile of various organism involved in causing urinary tract infection.Thus, this study aimed to determine the bacteriologic agents causing UTI and to evaluate their in vitro susceptibility pattern Material and Methods: Urine sample from 2100 patients with clinical symptoms of UTI were collected.Pure isolated bacteria were identified using biochemical tests and subjected to antimicrobial susceptibility testing using disc diffusion method as per CLSI guidelines.Results: Escherichia coli 114(57.3%)was the predominant organism followed by Klebsiella pneumoniae 22(11.1%)and enterococcus fecalis 19(9.5 %).E. coli resistance to various antibiotics were as follows, cotrimoxazole (67.5%) , norfloxacin (66.6%), cefoperazone/sulbactam (57%), piperacillin/tazobactam (50.8%), nitrofurantoin (35%), ertapenem(33.3%),gentamicin and meropenem (32.4%), ciprofloxacin (23.6%) imipenem (14%) and amikacin (13.1%) .K. pneumoniae showed resistance to cotrimoxazole (77.2%) , nitrofurantoin (72.7%), cefoperazone/sulbactam (68.1%), gentamicin (54.5%),…
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