Impact of diabetes on urinary tract infections sensitive and resistance to antibiotics
Abstract
The presence of a high level of sugar in the urine of diabetes patients creates an environment that is conducive to the colonization of bacteria, which in turn causes the bladder to become lazy, which further encourages the growth of bacteria.Antimicrobial resistance (AMR) and urinary tract infections (UTIs) have emerged as global public health issue.People with diabetes are more likely to get infections, and the increased antibiotic use among this population increases the likelihood that bacteria will develop resistance to these drugs.Patients with diabetes mellitus (DM) had 60 urine samples taken., 38 different bacteria were diagnosed and the sensitivity test of different antibiotics was studied using the Vitek-2 device to different bacteria.Results revealed that (55%) isolates were resistant to Amoxicillin /calvulanic acid, (56%) were resistant to ciprofloxacin; additionally, 47%, 42%, 39%, 36% and 34% isolates were resistant to Piperacillin tazobactam, levofloxacin, aztreonam, gentamicin, and Trimethoprim/sulfamethoxazole, respectively.While Meropenem and Imipenem were revealed to be most effective drug, it recorded the maximum sensitivity percentage77% and Amikacin 73%.The most effective antimicrobial agents against bacteria were those used against Escherichia coli then that used against Staphylococcus pseudomedius (Aztreonam, Imipenem, Meropenem, Amikacin), Klebsiella pneumonia (Gentamicin, Ciprofloxacin, Trimethoprim/Sulfamethoxazole), and
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.