A study of the clinico-demographical profile of urinary tract infections in carcinoma cervix
Abstract
Objectives: Understanding the clinical and demographic profile of urinary tract infections in cervical cancer patients, including risk factors, microbial spectrum, and antibiotic resistance patterns, is crucial for improving therapeutic strategies. Material and Methods: Following the approval by the Institutional Ethics Committee, all histologically confirmed cervical cancer patients registered in 2024 at our institution were reviewed retrospectively. Data were recorded on a structured proforma covering demographics, symptoms, risk factors, clinical parameters, routine laboratory examination, and culture sensitivity study of urine. Urinary tract infection (UTI) was defined by ≥10 5 CFU/mL growth. IBM SPSS Statistics for Windows, version 20.0, was used for statistical analysis. Results: A total of 187 histologically confirmed cervical cancer patients were studied, out of a total of 218 cervical cancer patients after excluding ineligible cases. Urine examination was performed in 151 (80.7%) patients, and 52 (27.8%) had culture-confirmed UTIs. The majority of infections (78.8%) were detected before commencing cancer treatment. Postmenopausal women faced the highest UTI risk (64.1% vs. 4.7% in premenopausal women; OR = 35.97, p <0.001, phi = 0.640). Albuminuria increased risk to 41.2% (OR = 4.06, p = 0.012, phi = 0.202), and hydronephrosis to 31.1% (OR = 3.11, p = 0.004, phi = 0.209). International Federation of Gynaecology and Obstetrics (FIGO) Stage IIIB was associated with a…
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