Microbial Etiology and Antibiotic Sensitivity Patterns of Urinary Tract Infections in a Tertiary Care Hospital
Abstract
Background: Urinary tract infections (UTIs) are a significant health concern worldwide, with varying microbial etiology and antibiotic sensitivity patterns. This study is designed to determine the microbial etiology and antibiotic sensitivity patterns of UTIs in a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted in the Department of Urology at Lady Reading Hospital in Peshawar. A total of 100 patients with signs and symptoms of UTIs were selected using purposive consecutive sampling. Urine cultures and antibiotic sensitivity testing were performed to identify the causative organisms and their sensitivity patterns. Results: E. coli was the most common microorganism isolated from urine cultures, accounting for 49.4% of the cases. Klebsiella pneumoniae and Pseudomonas aeruginosa were the second and third most common organisms, respectively. E. coli showed highest sensitivity to fosfomycin (79.1%), nitrofurantoin (74.4%), and amikacin (69.8%). High resistance was observed to fluoroquinolones (ciprofloxacin and levofloxacin), beta-lactams (co-amoxiclav), and third-generation cephalosporins (cefotaxime and ceftriaxone). Conclusion: The study highlights the importance of knowing the local microbiological profile and antibiotic sensitivity patterns in the management of UTIs. The findings suggest that fosfomycin, nitrofurantoin, and amikacin are effective antibiotics for the treatment of UTIs, while fluoroquinolones and cephalosporins may not be…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 100 participants or records.
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.