Burning of bacteria and antibiotic resistance and sensitivity in urinary tract infection: A single-center study
Abstract
Background:
Urinary Tract Infections (UTIs) are among the most frequent bacterial infections, primarily affecting women but also occurring in individuals of all genders and age groups. These infections arise when harmful microorganisms enter the urinary tract, causing symptoms that range from mild urinary discomfort to severe, potentially fatal conditions, such as sepsis.
Aim:
This study aimed to identify the bacterial pathogens responsible for UTIs and evaluate their antibiotic resistance and sensitivity profiles, which are key factors influencing treatment success. Additionally, the research compared two commonly used laboratory techniques, manual disc diffusion and the automated VITEK®2 system, to assess their reliability in detecting antibiotic resistance patterns in clinical isolates from patients with UTI.
Methods:
A total of 550 urine samples were collected from symptomatic patients at the Central Laboratory in Duhok. Bacterial identification was performed using biochemical tests and was confirmed using the VITEK®2 system. Antibiotic susceptibility testing was conducted using both the disc diffusion method and the VITEK®2 system, with 190 samples analyzed using the latter for comparison.
Results:
Of the samples analyzed, 249 patients were confirmed to have UTIs. The most commonly isolated bacteria were Staphylococcus epidermidis (26.9%), Staphylococcus aureus (20.1%), Escherichia coli (16.5%), Streptococcus pyogenes (5.6%), and Pseudomonas aeruginosa (2.8%). The…
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