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Reducing Recurrent Urinary Tract Infections in Women with MV140 Impacts Personal Burden of Disease: Secondary Analyses of a Randomized Placebo-controlled Efficacy Study

J. Nickel, Stephen J. Foley, Bob Yang, M. Casanovas, Raquel Caballero, Carmen M. Diez-Rivero, M. Lorenzo-Gómez

European Urology Open Science, 2024

10 citations

Abstract

Take Home Message A secondary analysis of a randomized placebo-controlled trial of MV140 vaccine demonstrating a reduction of recurrent urinary tract infection (UTI) in women showed an associated reduction in the personal burden of disease with a reduction of UTI symptoms and antibiotics, and improvement in quality of life.

How strong is the evidence?

Evidence Hub reads this as a secondary / pooled analysis, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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