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Klebsiella pneumoniae urinary tract infection: A multicentric study highlights significant regional variations in antimicrobial susceptibility across India

Meher Rizvi, Shalini Malhotra, Hiba Sami, Jyotsna Agarwal, A. H. Siddiqui, S. Devi, A. Poojary, B. Thakuria et al.

IJID Regions, 2025

5 citations

Abstract

Highlights • Mapping of the antimicrobial susceptibility of Klebsiella pneumoniae in urinary tract infection was undertaken by 18 centers across India.• The national susceptibilities to nitrofurantoin, meropenem, and fosfomycin were 39%, 81%, and 89%, respectively.• The proportion of susceptibility of K. pneumoniae to different antimicrobials was directly linked to geographic region (P <0.001).• South India had the highest mean susceptibility to trimethoprim/sulfamethoxazole, piperacillin/tazobactam, imipenem, and meropenem.• Humidity, and low and high temperatures (P <0.05) had a statistically significant effect on the proportion of susceptible K. pneumoniae.

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