Use of antibiotics for urinary tract infections up to and after care home admission in Denmark: a nationwide study
Abstract
To describe use-patterns of UTI antibiotics two years prior to and following care home admission in Denmark. Use of antibiotics for urinary tract infections double about six months prior to care home admission. Following care home admission, the use of antibiotics for urinary tract infection remains at a persistent high level. Use of antibiotics for urinary tract infections shows an overall decrease throughout the years 2016 to 2021, despite variation between residents, care homes, and geographical regions. Older people have the highest use of antibiotics for acute and chronic urinary tract infection (UTI), despite diagnostic uncertainty and the growing problem of antibiotic resistance. We aim to describe use-patterns of UTI antibiotics two years prior to and following care home admission in Denmark. This was a register-based nationwide drug-utilization study. In a cohort comprising all Danish residents admitted into a care home from 2015 to 2021, we described the use of UTI antibiotics, and examined differences between regions and individual care homes in rates of UTI antibiotic use. Further, we described trends in UTI-related contacts with hospitals in the two years prior to and following care home admission. The cohort comprised 101,297 residents (61% female; median age 84 years). UTI antibiotic use doubled from 7 to 14 treatments/100 residents/month two months prior to care home admission and remained at 10 treatments/100 residents/month the following two years.…
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.
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